Glutamate Receptor 1 anticorps (pThr856) (HRP)

N° du produit ABIN1711771

Cet anticorps Lapin Polyclonal détecte spécifiquement Glutamate Receptor 1 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour Glutamate Receptor 1 anticorps (pThr856) (HRP) (ABIN1711771)

Antigène: Glutamate Receptor 1 (GLUR1)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Glutamate Receptor 1 anticorps (HRP)

Épitope: pThr856

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Glutamate Receptor 1 around the phosphorylation site of Thr856

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GluR1

Sujet:

Synonyms: Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1, GRIA1, GLUH1, GLUR1

Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

ID gène: 2890

Pathways: Signalisation PI3K-Akt